Construct and interpret negative feedback loops

Construct and interpret negative feedback loops that show homeostasis by using a range of sources, including but not limited to: (ACSBL101, ACSBL110, ACSBL111)

  • Temperature (ACSBL098)
  • Glucose

Homeostasis:

  • Processes by which biological systems maintain stability and equilibrium by controlling different factors that play direct role for survival (temperature, pH, different chemicals etc).

Negative Feedback Loops:

  • Collection of processes that minimize/counteract the effect that causes disbalance in the normal body conditions.
  • Mechanism involves opposing the condition that caused the normal body condition to deviate.
  • Generally, a signal of change is sent to the control centre which in response, activates effectors which oppose the stimulus.

Temperature Homeostasis by Negative Feedback Loop:

  • Rise or fall in the temperature is detected by sensors that relay this message to the temperature regulation centre of the brain located in the hypothalamus.
  • Responses may occur in the following ways:
Temperature RiseTemperature Fall
Vasodilation: Arterioles dilate (enlarge) so more blood enters skin capillaries and heat is lost.Vasoconstriction: Arterioles get smaller to reduce blood going to skin: keeping core warm.
Sweating: Sudorific glands secrete sweat which removes heat when water changes state.Shivering: Rapid contraction and relaxing of skeletal muscles. Heat produced by respiration.
Pilorelaxation: This means the hairs flatten.Piloerection: Hairs on skin stand up.
Stretching Out: By opening up, the body was a larger surface area.Curling Up: Making yourself smaller so smaller surface area.

Glucose Homeostasis by Negative Feedback Loop:

  • Blood glucose level is controlled by hormones produced in the pancreas in the Islets of Langerhans.
  • After intake of food, glucose level increases in blood which is detected by Beta Cells in the Islets of Langerhans.
  • Beta Cells produce a hormone called Insulin.
  • Insulin acts as a signal that triggers cells of the body, such as fat and muscle cells, to take up glucose for using as fuel.
  • Insulin also encourages glycogenesis.
  • If our body lacks glucose, Alpha cells produce Glucagon that convert glycogen to glucose and maintains blood sugar level.

 

Extract from HSC Biology Stage 6 Syllabus. © 2017 Board of Studies NSW.

EasyBio > Non-infectious Disease and Disorders > Homeostasis > Construct and interpret negative feedback loops


Construct and interpret negative feedback loops that show homeostasis by using a range of sources, including but not limited to: (ACSBL101, ACSBL110, ACSBL111)

  • temperature (ACSBL098)
  • glucose

Homeostasis:

  • Processes by which biological systems maintain stability and equilibrium by controlling different factors that play direct role for survival (temperature, pH, different chemicals etc).

Negative Feedback Loops:

  • Collection of processes that minimize/counteract the effect that causes disbalance in the normal body conditions.
  • Mechanism involves opposing the condition that caused the normal body condition to deviate.
  • Generally, a signal of change is sent to the control centre which in response, activates effectors which oppose the stimulus.

Temperature Homeostasis by Negative Feedback Loop:

  • Rise or fall in the temperature is detected by sensors that relay this message to the temperature regulation centre of the brain located in the hypothalamus.
  • Responses may occur in the following ways:
Temperature RiseTemperature Fall
Vasodilation: Arterioles dilate (enlarge) so more blood enters skin capillaries and heat is lost.Vasoconstriction: Arterioles get smaller to reduce blood going to skin: keeping core warm.
Sweating: Sudorific glands secrete sweat which removes heat when water changes state.Shivering: Rapid contraction and relaxing of skeletal muscles. Heat produced by respiration.
Pilorelaxation: This means the hairs flatten.Piloerection: Hairs on skin stand up.
Stretching Out: By opening up, the body was a larger surface area.Curling Up: Making yourself smaller so smaller surface area.

Glucose Homeostasis by Negative Feedback Loop:

  • Blood glucose level is controlled by hormones produced in the pancreas in the Islets of Langerhans.
  • After intake of food, glucose level increases in blood which is detected by Beta Cells in the Islets of Langerhans.
  • Beta Cells produce a hormone called Insulin.
  • Insulin acts as a signal that triggers cells of the body, such as fat and muscle cells, to take up glucose for using as fuel.
  • Insulin also encourages glycogenesis.
  • If our body lacks glucose, Alpha cells produce Glucagon that convert glycogen to glucose and maintains blood sugar level.

Extract from HSC Biology Stage 6 Syllabus. © 2017 Board of Studies NSW.